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How should I take Diazepam?


Valium (Diazepam)

What is diazepam?

Diazepam, first marketed as Valium, is a medication of the benzodiazepine family that typically produces a calming effect. It is commonly used to treat a range of conditions including anxiety, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, seizures, trouble sleeping, and restless legs syndrome.It may also be used to cause memory loss during certain medical procedures.Diazepam may also be used for purposes not listed in this medication guide. To buy Diazepam at 24hrspharma, go here.

It can be taken by mouth, inserted into the rectum, injected into muscle, or injected into a vein. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects may take 40 minutes to begin.

How should I take diazepam?

Take diazepam exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Diazepam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Diazepam should be used for only a short time. Do not take this medicine for longer than 4 months without your doctor's advice.

Do not stop using diazepam suddenly, or you could have increased seizures or unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Call your doctor at once if you feel that this medicine is not working as well as usual, or if you think you need to use more than usual.

While using diazepam, you may need frequent blood tests at your doctor's office.

Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Diazepam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Dosing and Administration

In treatment of severe diseases of central nervous system Valium (Diazepam) is used under medical supervision. If you have never used strong muscle relaxants and do not know how they operate, it is recommended to consult your doctor and to find out the dosing regimen and recommendations for use.

-     For adults, the optimal dose is 10 mg 2 times a day, in the morning and evening

-     The maximum daily dose for adults is 20 mg 3 times a day, prescribed in cases of nervous system severe disorders under the supervision of a physician.

-     Children from 2 to 5 mg 2-3 times a day, depending on the age and type of disorder.

-     The dosage for children should not exceed 15 mg per day.

What should I avoid while taking diazepam?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Do not drink alcohol while taking diazepam. This medication can increase the effects of alcohol.

Grapefruit and grapefruit juice may interact with diazepam and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.

Important information

You should not use this medicine if you are allergic to diazepam or similar medicines (Ativan, Klonopin, Restoril, Xanax, and others), or if you have myasthenia gravis, severe liver disease, narrow-angle glaucoma, a severe breathing problem, or sleep apnea.

Before you take diazepam, tell your doctor if you have glaucoma, asthma or other breathing problems, kidney or liver disease, seizures, or a history of drug or alcohol addiction, mental illness, depression, or suicidal thoughts.

Do not start or stop taking diazepam during pregnancy without your doctor's advice. Diazepam may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking diazepam for seizures.

Diazepam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not give this medication to a child younger than 6 months old.

Before taking this medicine

You should not use this medicine if you are allergic to diazepam or similar drugs (Ativan, Klonopin, Restoril, Xanax, and others), or if you have:

  • myasthenia gravis (a muscle weakness disorder);
  • severe liver disease;
  • a severe breathing problem;
  • sleep apnea (breathing stops during sleep); or
  • alcoholism, or addiction to drugs similar to diazepam.

To make sure diazepam is safe for you, tell your doctor if you have any of these conditions:

  • glaucoma;
  • asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
  • kidney or liver disease;
  • epilepsy or other seizure disorder;
  • a history of mental illness, depression, or suicidal thoughts or behavior; or
  • a history of drug or alcohol addiction.

When treating seizures, do not start or stop taking diazepam during pregnancy without your doctor's advice. Diazepam may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking diazepam for seizures.

When treating anxiety, alcohol withdrawal, or muscle spasms: If you take diazepam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Diazepam can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

The sedative effects of diazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking this medicine.

Diazepam is not approved for use by anyone younger than 6 months old. Do not give this medicine to a child without a doctor's advice.

 

Possible Diazepam side effects

Get emergency medical help if you have signs of an allergic reaction to diazepam: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • confusion, hallucinations, unusual thoughts or behavior;
  • unusual risk-taking behavior, decreased inhibitions, no fear of danger;
  • depressed mood, thoughts of suicide or hurting yourself;
  • hyperactivity, agitation, aggression, hostility;
  • new or worsening seizures;
  • weak or shallow breathing, a feeling like you might pass out;
  • muscle twitching, tremor;
  • loss of bladder control; or
  • little or no urinating.

Common diazepam side effects may include:

  • drowsiness;
  • tired feeling;
  • muscle weakness; or
  • loss of coordination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. 

What other drugs will affect diazepam?

Taking diazepam with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking diazepam with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • cimetidine;
  • disulfiram (Antabuse);
  • omeprazole;
  • phenytoin;
  • an antibiotic--clarithromycin, erythromycin, telithromycin;
  • an antidepressant such as fluoxetine and others;
  • antifungal medicine--itraconazole, ketoconazole, voriconazole;
  • heart or blood pressure medication such as diltiazem, nicardipine, quinidine, verapamil, and others; or
  • HIV/AIDS medicine--atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, saquinavir, or ritonavir.

This list is not complete. Other drugs may interact with diazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diazepam can be fatal.

Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, or fainting.

 

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Anyone who is suffering from serious anxiety problems, muscle spasms, seizure disorders, alcoholic withdrawal, or short term insomnia knows how hard it can be to deal with these things without the help of some prescription medication. Valium is a medication that can offer much needed relief. There is only one issue though that prevents people from getting it.

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The aim has to be thins, buying Valium without prescription and keeping your risk down. You do not want to risk losing your money, getting a bad product, or having the online pharmacy you do business with disappear over night. So what is the solution to this? Well the best solution is to find the biggest and most well known online pharmacy to do business with.

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These places are willing to protect you the consumer and make sure you get what you are paying for. The places where you will be able to get Valium without prescription that are reputable will have the drug available to you in different amounts as well. You can order large sizes and save money or you can just get however much you feel you need.

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Valium without prescription is a risk that people are willing to take because they need help, and it is being denied to them. Just make sure you keep safe if you go this route. Make sure you take only what you need and be sure you do not plan on taking the medication long term. Long term use is just too risky without consulting with a doctor.

 

Drug Uses

Valium (Diazepam) can be used not only to treat seizures, but also for:

-     Neurosis

-     Psychopaths

-     Anxiety Disorders

-     Panic fear

-     Increased irritability

-     Epilepsy

-     Phobias

-     Conduct Disorder

Despite the fact that this drug has antidepressant properties, it has a general sedative and relaxing effect which positively affects patient’s central nervous system, and quickly cope with the symptoms of nervous system disorders.

Recommendations for use

-     In the first few days of taking the drug, the patient may suffer from lethargy and drowsiness, so it is advisable to limit activities that require special attention.

-     Valium (Diazepam) intensifies ethyl alcohol activity in the body, so you should not use alcohol while taking these pills.

 

Precautions 

-     As a result of the prolonged use of high doses of Valium (Diazepam), the patient may develop addiction, so it is not advisable to take the drug for a long time, without any clinical indications.

-     Valium (Diazepam) is contraindicated in case of: shock conditions, glaucoma, alcohol intoxication, acute liver disease or kidney disease, the symptoms of the central nervous system depression, as well as in acute respiratory failure.

-     This drug is contraindicated for children younger than 1 year old, pregnant women.

-     If a woman is forced to take the drug during lactation, it is necessary to stop breastfeeding temporarily.

 

Side Effects

Side effects of Valium (Diazepam) can be observed within the first few days of treatment. Most common side effects are: dizziness, drowsiness, lethargy, weakness, fatigue, decreased coordination, and slowing of psychomotor reactions. Most of the side effects are short-term and will gradually disappear, so the patient continues the treatment, without discomforts. 

This drug depresses the central nervous system when using with other drugs and side effects may be amplified, so you need to reduce the single dose of Valium (Diazepam).

Disclaimer

• Information provided in this article is for only general knowledge and is not a guide to action. The creators of this web site only provide information that you need to know for safe use of drugs, but it is strongly recommended to consult an expert doctor before you start taking any medication.

 

See also: Side effects (in more detail)

Diazepam dosing information

Usual Adult Dose for Anxiety:

Oral: 2 to 10 mg 2 to 4 times a day.
IM or IV: 2 to 5 mg (moderate anxiety) or 5 to 10 mg (severe anxiety) for one dose. May repeat in 3 to 4 hours, if necessary.

Usual Adult Dose for Alcohol Withdrawal:

Oral: 10 mg 3 to 4 times during the first 24 hours, then 5 mg 3 to 4 times a day as needed.
IM or IV: 5 to 10 mg one time. May repeat in 3 to 4 hours, if necessary.

Usual Adult Dose for ICU Agitation:

Initial dose: 0.02 to 0.08 mg/kg IV over 2 to 5 minutes every 0.5 to 2 hours to control acute agitation.
Maintenance dose: 0.4 to 0.2 mg/kg/hr by continuous IV infusion.

Usual Adult Dose for Muscle Spasm:

Oral: 2 to 10 mg 3 to 4 times a day.
IM or IV: 5 to 10 mg initially, then 5 to 10 mg in 3 to 4 hours, if necessary. For tetanus, larger doses may be required.

Usual Adult Dose for Seizures:

Oral: 2 to 10 mg 2 to 4 times a day.
Rectal gel: 0.2 mg/kg, rounded up to the nearest available unit dose. A supplemental dose of 2.5 mg may be added for more precise titration or if a portion of the first dose is expelled. May repeat in 4 to 12 hours. Maximum of 1 episode every 5 days, or 5 episodes per month.

Usual Adult Dose for Endoscopy or Radiology Premedication:

IV: 10 mg or less is usually adequate; however up to 20 mg may be necessary to produce the desired sedation in some patients.
IM: If IV cannot be used, 5 to 10 mg 30 minutes prior to the procedure.
Dosage of narcotics should be reduced by at least a third and in some cases may be omitted.

Usual Adult Dose for Status Epilepticus:

IV or IM: 5 to 10 mg initially (IV preferred).
May be repeated at 10 to 15 minute intervals up to a maximum dose of 30 mg.
If necessary, may be repeated again in 2 to 4 hours.

Usual Adult Dose for Light Anesthesia:

Premedication for Anesthesia:
10 mg, IM (preferred route), 1 to 2 hours before surgery.

Usual Pediatric Dose for Seizures:

Rectal gel:
Infants less than 6 months old: Not recommended; product contains benzoic acid, benzyl alcohol, ethanol 10%, propylene glycol, and sodium benzoate. Prolonged CNS depression has been reported in neonates receiving diazepam.
Infants and Children 6 months to 2 years: Dose not established
2 to 5 years: 0.5 mg/kg, rounded up to the nearest available unit dose.
6 to 11 years: 0.3 mg/kg, rounded up to the nearest available unit dose.
12 years or greater: 0.2 mg/kg, rounded up to the nearest available unit dose.
A supplemental dose of 2.5 mg may be added in 10 minutes for more precise titration or if a portion of the first dose is expelled. May repeat in 4 to 12 hours. Maximum of 1 episode every 5 days, or 5 episodes per month.

Usual Pediatric Dose for Status Epilepticus:

Neonates: IV: (This is not recommended as a first line agent because the injection contains benzoic acid, benzyl alcohol, and sodium benzoate): 0.1 to 0.3 mg/kg/dose given over 3 to 5 minutes, every 15 to 30 minutes to a maximum total dose of 2 mg.

Infants greater than 30 days old and Children: IV: 0.1 to 0.3 mg/kg dose given over 3 to 5 minutes, every 5 to 10 minutes (maximum of 10 mg/dose).

Manufacturer recommendation:

Infants greater than 30 days old and Children less than 5 years: IV: 0.2 to 0.5 mg slow IV every 2 to 5 minutes up to a maximum total dose of 5 mg. Repeat in 2 to 4 hours if needed.

Children greater than or equal to 5 years: IV: 1 mg slow IV every 2 to 5 minutes up to a maximum of 10 mg. Repeat in 2 to 4 hours if needed.

Usual Pediatric Dose for Anxiety:

1 to 12 years:
Oral: 0.12 to 0.8 mg/kg/day in divided doses every 6 to 8 hours as needed.

IM: 0.04 to 0.3 mg/kg every 2 to 4 hours as needed, up to a maximum of 0.6 mg/kg in 8 hours.

Febrile seizure prophylaxis in children: Oral: 1 mg/kg/day orally in divided doses every 8 hours. Initiate therapy at first sign of fever and continue for 24 hours after fever resolves.

Usual Pediatric Dose for Muscle Spasm:

1 to 12 years:
Oral: 0.12 to 0.8 mg/kg/day in divided doses every 6 to 8 hours as needed.

IM: 0.04 to 0.3 mg/kg every 2 to 4 hours as needed, up to a maximum of 0.6 mg/kg in 8 hours.

Febrile seizure prophylaxis in children: Oral: 1 mg/kg/day orally in divided doses every 8 hours. Initiate therapy at first sign of fever and continue for 24 hours after fever resolves.

Usual Pediatric Dose for Seizure Prophylaxis:

1 to 12 years:
Oral: 0.12 to 0.8 mg/kg/day in divided doses every 6 to 8 hours as needed.

IM: 0.04 to 0.3 mg/kg every 2 to 4 hours as needed, up to a maximum of 0.6 mg/kg in 8 hours.

Febrile seizure prophylaxis in children: Oral: 1 mg/kg/day orally in divided doses every 8 hours. Initiate therapy at first sign of fever and continue for 24 hours after fever resolves.

Usual Pediatric Dose for Light Sedation:

Conscious sedation for procedures:
Oral:
1 to 12 years: 0.2 to 0.3 mg/kg orally 45 to 60 minutes before procedure, up to a maximum of 10 mg
13 to 18 years: 5 mg orally 45 to 60 minutes before procedure, may repeat with 2.5 mg dose.

Sedation:
1 to 12 years:
Oral: 0.02 to 0.3 mg/kg every 6 to 8 hours as needed.
IM: 0.04 to 0.3 mg/kg IM every 2 to 4 hours as needed, up to a maximum of 0.6 mg/kg in 8 hours.

13 to 18 years:
Oral: 2 to 10 mg 2 to 4 times a day as needed.
IM or IV: 2 to 10 mg 2 to 4 times a day as needed.

Usual Pediatric Dose for Tetanus:

Less than 1 month: 0.83 to 1.67 mg/kg/hour by continuous IV infusion, or 1.67 to 3.33 mg/kg IV, slowly, every 2 hours (20 to 40 mg/kg/day). Diazepam injection is not recommended as the drug of choice for neonates due to its benzyl alcohol and propylene glycol content.

1 month to 5 years: 1 to 2 mg IM or IV, slowly, repeated every 3 to 4 hours as necessary, or 15 mg/kg/day in divided doses every 2 hours.

Greater than 5 years: 5 to 10 mg IM or IV, slowly, repeated every 3 to 4 hours as necessary.

 



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