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How do I buy cheap Provigil / Modafinil?


What is Provigil / Modafinil and where do I buy it online?

Provogil and generic Modafinil is a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: narcolepsy, obstructive sleep apnea (OSA), or shift work disorder (SWD).

Provigil and generic Modafinil is used to treat excessive sleepiness, but not the obstruction or medical condition that is causing OSA. Provigil and generic Modafinil does not take the place of treatments that your doctor has prescribed for OSA. It is important that you continue to use these treatments as prescribed by your doctor.

Provigil and generic Modafinil will not cure these sleep disorders. Provigil and generic Modafinil may help the sleepiness caused by these conditions, but it may not stop all your sleepiness. Provigil and generic Modafinil does not take the place of getting enough sleep.

Provigil and generic Modafinil is a federally controlled substance (C-IV) because it can be abused or lead to dependence. Keep Provigil and generic Modafinil in a safe place to prevent misuse and abuse. Selling or giving away Provigil and generic Modafinil may harm others, and is against the law.

Modafinil is a wakefulness-promoting agent (or eugeroic) used for treatment of disorders such as narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea.It has also seen widespread off-label use as a purported cognition-enhancing agent. In English-speaking countries it is sold under the brand names Alertec, Modavigil, and Provigil. In the United States Modafinil is classified as a schedule IV controlled substance and restricted in availability and usage, due to concerns about possible addiction potential. In most other countries it is a prescription drug but not otherwise legally restricted.

Although the mechanism of action of Modafinil was initially unknown, it now appears that drug acts as a selective, relatively weak, atypical dopamine reuptake inhibitor, a notion that is supported by an abundance of evidence. However, it appears that other, additional mechanisms may also be at play.

Modafinil is a wakefulness-promoting agent (or eugeroic) used for treatment of narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea.

Because of the risk for development of skin or hypersensitivity reactions and neuropsychiatric disorders, the European Medicines Agency has recommended that new patient prescriptions should only be to treat sleepiness associated with narcolepsy.

Off-label use for fatigue

Modafinil has also found off-label use with the neurological fatigue reported by some with multiple sclerosis.In 2000, Cephalon conducted a study to evaluate Modafinil as a potential treatment for MS-related fatigue. A group of 72 people with MS of varying degrees of severity tested two different doses of Modafinil and an inactive placebo over nine weeks. Fatigue levels were self-evaluated on standardized scales. Participants taking a lower dose of Modafinil reported feeling less fatigued and there was a statistically significant difference in fatigue scores for the lower dose versus the placebo. The higher dose of Modafinil was not reported to be significantly more effective.

Modafinil is also used off-label to treat sedation and fatigue in many conditions, including depression, fibromyalgia, chronic fatigue syndrome, myotonic dystrophy, opioid-induced sleepiness, spastic cerebral palsy,and Parkinson's disease. Modafinil has been shown to improve excessive daytime somnolence and fatigue in primary biliary cirrhosis.

Military and astronauts and the use of Modafinil

Militaries of several countries are known to have expressed interest in Modafinil as an alternative to amphetamine—the drug traditionally employed in combat situations where troops face sleep deprivation, such as during lengthy missions. The French government indicated that the Foreign Legion used Modafinil during certain covert operations.The United Kingdom's Ministry of Defence commissioned research into Modafinil from QinetiQ and spent £300,000 on one investigation.In 2011, the Indian Air Force announced that Modafinil was included in contingency plans.

In the United States military, Modafinil has been approved for use on certain Air Force missions, and it is being investigated for other uses. As of November 2012, Modafinil is the only drug approved by the Air Force as a "go pill" for fatigue management.The use of dextroamphetamine (a.k.a., Dexedrine) is no longer approved.

The Canadian Medical Association Journal also reports that Modafinil is used by astronauts on long-term missions aboard the International Space Station. Modafinil is "available to crew to optimize performance while fatigued" and helps with the disruptions in circadian rhythms and with the reduced quality of sleep astronauts experience.

How to use Modafinil:

Use Modafinil as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Modafinil comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Modafinil refilled.
  • Take Modafinil by mouth with or without food.
  • Take Modafinil in the morning unless otherwise directed by your doctor.
  • If you take Modafinil for shift work sleep problems, take about 1 hour before the start of work.
  • If you miss a dose of Modafinil, take it as soon as possible. If you do not remember until late afternoon or evening, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Modafinil.

Usual Adult Dose for Narcolepsy

200 mg orally once a day in the morning

Comments:
-In obstructive sleep apnea (OSA), this drug is not a treatment for the underlying obstruction.
-If continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to and during treatment with this drug.

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with narcolepsy and OSA.

Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome

200 mg orally once a day in the morning

Comments:
-In obstructive sleep apnea (OSA), this drug is not a treatment for the underlying obstruction.
-If continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to and during treatment with this drug.

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with narcolepsy and OSA.

Usual Adult Dose for Shift Work Sleep Disorder

200 mg orally once a day, approximately 1 hour prior to the start of the work shift

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with shift work disorder.

Do NOT use Modafinil if:

  • you are allergic to any ingredient in Modafinil or to arModafinil
  • you have a history of developing a rash after taking Modafinil or arModafinil
  • you have a history of certain heart or heart valve problems (eg, mitral valve prolapse, left ventricular hypertrophy)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Modafinil:

Some medical conditions may interact with Modafinil. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems, kidney problems, heart problems (eg, chest pain, heart blood vessel problems, a recent heart attack), or high blood pressure
  • if you have a history of mental or mood problems (eg, depression, mania, psychosis), suicidal thoughts or actions, or alcohol or other substance abuse or dependence
  • if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine)

 

Some MEDICINES MAY INTERACT with Modafinil. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Erythromycin or ketoconazole because they may increase the risk of Modafinil's side effects
  • Carbamazepine, phenobarbital, or rifampin because they may decrease Modafinil's effectiveness
  • Clomipramine, desipramine, diazepam, hydantoins (eg, phenytoin), omeprazole, propranolol, or warfarin because the risk of their side effects may be increased by Modafinil
  • Cyclosporine, hormonal products (eg, birth control pills, certain hormone replacements), midazolam, quetiapine, or triazolam because their effectiveness may be decreased by Modafinil

 

This may not be a complete list of all interactions that may occur. Ask your health care provider if Modafinil may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

What are possible side effects of generic Nuvigil / Armodafinil?

NUVIGIL may cause serious side effects. Stop taking NUVIGIL and call your doctor right away or get emergency help if you get any of the following:

  • a serious rash or serious allergic reaction (see above)
  • mental (psychiatric) symptoms, including: depression; feeling anxious; hearing, seeing, feeling, or sensing things that are not really there (hallucinations); an extreme increase in activity and talking (mania); thoughts of suicide; aggressive behavior, and other mental problems
  • symptoms of a heart problem, including chest pain, abnormal heart beats, and trouble breathing.

 

Common side effects of NUVIGIL include headache, nausea, dizziness, and trouble sleeping.

Tell your doctor if you get any side effect that bothers you or that does not go away while taking NUVIGIL.

These are not all the side effects of NUVIGIL. Below is a more complete list of possible side effects:

Please remember that this information does not take the place of talking with your doctor for medical advice about your condition or treatment.

A detailed list of possible side effects of generic Nuvigil / Armodafinil

This information applies to Armodafinil in the following format: Oral tablet

Severity: Major

If any of the following side effects occur while taking Armodafinil, check with your doctor immediately:

Less common

  • Blistering, burning, crusting, dryness, or flaking of the skin
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • difficult or labored breathing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • frequent urination
  • headache, severe and throbbing
  • increased volume of pale, dilute urine
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • rash
  • shakiness in the legs, arms, hands, or feet
  • shortness of breath
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • wheezing

 

If any of the following symptoms of overdose occur while taking Armodafinil, get emergency help immediately:

Symptoms of overdose

  • Anxiety
  • blurred vision
  • chest pain or discomfort
  • confusion about identity, place, and time
  • diarrhea
  • dry mouth
  • headache
  • hyperventilation
  • irritability
  • lightheadedness, dizziness, or fainting
  • nausea
  • nervousness
  • pounding in the ears
  • restlessness
  • seeing, hearing, or feeling things that are not there
  • sleeplessness
  • slow heartbeat
  • trouble sleeping
  • unable to sleep
  • unusual tiredness or weakness

 

Severity: Minor

Some Armodafinil side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common

  • Acid or sour stomach
  • belching
  • chills
  • cough
  • depression
  • difficulty having a bowel movement (stool)
  • discouragement
  • feeling sad or empty
  • general feeling of discomfort or illness
  • heartburn
  • indigestion
  • joint pain
  • loss of appetite
  • loss of interest or pleasure
  • mood or mental changes
  • muscle aches and pains
  • runny nose
  • shivering
  • sore throat
  • stomach discomfort, upset, or pain
  • sweating
  • thirst
  • tiredness
  • trouble concentrating
  • vomiting
  • weight loss

 



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